Infants display a wide range of liver problems ranging from age appropriate differences in laboratory values to both hepatocellular and cholestatic liver diseases and frank liver failure. Achieving a specific hepatology diagnosis can be challenging, as infants with disparate types of liver disease may present with overlapping clinical symptoms and nonspecific radiologic findings. Treatment and prognosis varies based on disease etiology, underscoring the importance of accurate diagnosis. This seminar will review the clinical presentations of liver abnormalities seen in the NICU along with diagnostic methodologies including routine labs/imaging, genetic testing, and liver biopsy. Management options and outcomes will be presented including liver transplant in infancy.
- Identify blood testing useful to distinguish categories of liver disease in infants
- Identify liver imaging useful in the assessment of neonatal cholestasis
- Describe the outcome of liver transplant in young infants
This seminar focuses on gastroenterology and was delivered at a virtual event titled, “The Gamut of NICU Liver Issues: from Elevated Bilirubin to Liver Transplant”, on April 21, 2021.
Additional CHOP Resources:
- Pediatric Transplant Center
- Division of Gastroenterology, Hepatology and Nutrition
- Upcoming Healthcare Professionals Events
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