Gene Therapy for Sickle Cell Disease
Sickle cell disease is an inherited blood disorder that often causes debilitating pain and life-threatening complications. Many patients with the disease make dozens of ER…
Course Category: Breaking Through with Madeline Bell
Mental Health Is Health: Caring for the Whole Child
The team at Children’s Hospital of Philadelphia (CHOP) believes that mental health is just as important as physical health – and they’re working together to…
Elijah’s Story: Navigating a Medical Mystery
From the time Elijah was a baby, he had many painful symptoms – and no one could determine what was wrong. But when Elijah was…
Tenlee’s Story: Thriving After a Heart Transplant
Tenlee was born with a rare heart condition and had a heart transplant at Children’s Hospital of Philadelphia when she was just 5 months old.…
Kareem’s Story: Advocating for Trauma-Informed Care
While growing up in West Philadelphia, Kareem saw firsthand the devastating impact trauma and violence can have on children. In this episode of The Breakthrough…
Hannah’s Story: Moving Beyond Blindness
When Hannah was a baby, she was diagnosed with a rare eye disease that usually leaves patients completely blind. But Hannah’s story turned out differently…
Emily’s Story: Celebrating 10 Years Cancer Free
Emily was just 6 years old when she received CAR T cell immunotherapy for relapsed leukemia at Children’s Hospital of Philadelphia. Emily was the very…
Conjoined Twins’ Separation Story
When Addy and Lily Altobelli were born in CHOP’s Garbose Family Special Delivery Unit, they needed highly specialized care because they were conjoined – their…
“Do What You Love”: Finding Medicines for Rare Diseases
Hematologist and oncologist Denise Adams, MD, specializes in treating vascular anomalies, which occur when arteries, capillaries, veins or lymphatic vessels fail to develop correctly. She…
“I’ve Always Loved to Ask Why”: The Power of Mitochondrial Medicine
Our mitochondria make the energy that keeps us alive. Geneticist Marni Falk, MD, joins Madeline to discuss what happens when our mitochondria don’t work properly,…